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THYROID
CANCER
Definition Thyroid cancer is a disease
in which the thyroid cells become abnormal, grow uncontrollably,
and form tumors. Thyroid cancers are grouped into four types,
based on how the cell appears under the microscope. If left
untreated, the cancer can spread to other parts of the body.
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SUBCLINICAL
THYROID DISEASE
Subclinical thyroid dysfunction is defined as an abnormal serum
thyroid-stimulating hormone level (reference range: 0.45 to 4.50
[micro]U per mL) and free thyroxine and triiodothyronine levels
within their reference ranges.
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SCREENING
FOR THYROID DISEASE
LF, a 50-year-old woman, requests a "thyroid blood test." You
review the symptoms of hypothyroidism and hyperthyroidism with her
and find that she has none of them. She still is concerned because
"a doctor on television said all women should have this test."
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THYROID FUNCTION TESTS
Definition Thyroid function tests are
blood tests used to evaluate how effectively the thyroid gland is
working. These tests include the thyroid-stimulating hormone test
(TSH), the thyroxine test (T4), the triiodothyronine test (T3),
the thyroxine-binding globulin test (TBG), the triiodothyronine
resin uptake test (T3RU), and the long-acting thyroid stimulator
test (LATS).
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PAPILLARY
THYROID CARCINOMA
Papillary thyroid carcinoma is the most common type of thyroid
malignancy. The minor occurs largely in adults, usually those
between the ages of 20 and 50 years; the female-to-male ratio is
4:1. Papillary thyroid carcinoma is also the most common pediatric
thyroid malignancy.
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THYROID
DISEASE IN CHILDREN
During embryogenesis, epithelial cells on the pharyngeal floor
thicken to form a diverticulum. This diverticulum elongates, and
the primordial thyroid cells migrate caudally until they fuse with
the ventral aspect of the fourth pharyngeal pouch, at about the
fourth gestational week
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THYROID
ULTRASOUND
Definition Thyroid ultrasound is an
imaging technique used for diagnosing suspected thyroid disease.
It uses harmless, high frequency sound waves to form an image. The
sound waves are reflected by thyroid tissue to form a picture of
internal structures. It is not invasive and involves no radiation.
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BLACK
THYROID - PATHOLOGY CLINIC
A finding of a black thyroid gland (figure 1) is unusual and
disconcerting. Among the possible causes of black thyroid are
minocycline-induced pigmentation, hemochromatosis, ochronosis,
mucoviscidosis, ceroid storage disease, bruising, and hemorrhage.
In addition, medullary thyroid carcinomas have been reported to
produce melanin in rare cases.
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